Depressed mood (sometimes shows up as irritability)

Loss of interest or pleasure in life (don't enjoy things you used to enjoy)

Significant change in appetite (up or down)

Abnormal changes in sleep pattern (too much or too little)

Fatigue or loss of energy

Feelings of worthlessness or inappropriate excessive guilt

Diminished ability to think or concentrate

Becoming indecisive or easily overwhelmed

Thoughts of death and suicide